While preparing for the presentation on Silverlight and SharePoint next week I've just discovered that the current Beta 1 of SilverLight 2 is unable to call SharePoint's native webservices.
The technical reason is that the WSDL SharePoint generates includes an asd:any declaration which is translated by the proxy generator as requiring the XmlElement class but Silverlight does not support this class. So you're not able to call GetList or GetListItems in Lists.asmx for instance.
I've posted on the Silverlight forums about this but the reply I got from Yavor Georgiev (Program Manager - Connected Services) was not clear as to whether this is a planned feature for SL 2.
There are a few ways around this which I'll go into in the presentation but none are very pleasant prospects.
There's probably still time to get this feature in v2. The best thing is to let MS know this is an important issue by adding support on the thread. Also worth keeping an eye on the Silverlight Web Services blog.